Translational Research: From Observational Studies to Health Policy

Translational research: from observational studies to health policy: how a cohort study can help improve outcomes after stroke.

Access to specialized care and primary prevention are associated with better outcomes in cardiovascular diseases.1,2 The burden of stroke, and vascular disease in general, is higher in lower-income countries where 82% of all cardiovascular deaths (14 million) occurs annually.3,4 For example, in emerging/low-middle income countries (ELMICs; those with low gross domestic product and health expend...

How to Produce Translational Research to Guide Arctic Policy

Translational Antidote Research: A Bedside to Bench Tale

Although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. The development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an example of how this may not be the case. Interest in the development of fomepizole was spurred in the 1960s. Shortly t...

Translational health research: perspectives from health education specialists

The phrase "from bench to bedside to curbside" is a common definition of translational research among health disparities researchers. Health Education Specialists can make important contributions to the field of clinical translational medicine, particularly in light of U.S. health care reform and a renewed emphasis on medical home or health care home models.Health Education Specialists have the...

Correct sampling in observational studies.

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